Zesty Cajun Garlic Parmesan Chicken

Featured in: Easy Weeknight Wins

This vibrant dish brings together juicy chicken, cheesy tortellini, and a luscious Cajun garlic Parmesan sauce. Quick to prepare, it’s ideal for weeknights, offering a fusion of American and Italian flavors with a spicy kick, plenty of cream, and nutty Parmesan. The sautéed bell pepper and onion create depth, while fresh parsley and extra cheese finish it beautifully. Serve with crusty bread and a crisp white wine for a satisfying, hearty meal that’s sure to please.

Updated on Sat, 08 Nov 2025 15:07:00 GMT
Creamy Zesty Cajun Garlic Parmesan Chicken Tortellini garnished with fresh parsley and cheese.  Save
Creamy Zesty Cajun Garlic Parmesan Chicken Tortellini garnished with fresh parsley and cheese. | tastyeffect.com

A vibrant and flavorful pasta dish featuring tender chicken, cheesy tortellini, and a creamy Cajun garlic Parmesan sauce. Perfect for a quick weeknight meal with a spicy kick.

I first made this Cajun garlic Parmesan chicken tortellini when craving something comforting but with a lively twist. The balance of spices and creamy sauce instantly made it a weeknight favorite in my kitchen.

Ingredients

  • Chicken breasts: 2 large boneless, skinless, cut into bite-sized pieces
  • Cheese tortellini: 500 g (18 oz), refrigerated
  • Garlic: 3 cloves, minced
  • Red bell pepper: 1 small, diced
  • Yellow onion: 1 small, diced
  • Heavy cream: 1 cup (240 ml)
  • Parmesan cheese: 1/2 cup (50 g), freshly grated
  • Unsalted butter: 2 tablespoons
  • Cajun seasoning: 1 tablespoon
  • Smoked paprika: 1/2 teaspoon
  • Black pepper: 1/2 teaspoon
  • Salt: 1/2 teaspoon, plus more to taste
  • Olive oil: 2 tablespoons
  • Fresh parsley: 2 tablespoons, chopped, for garnish
  • Optional extra Parmesan: For serving

Instructions

Cook Tortellini:
Bring a large pot of salted water to a boil. Cook tortellini according to package instructions. Drain and set aside.
Sauté Chicken:
Heat 1 tablespoon olive oil in a large skillet over medium-high heat. Add chicken pieces, season with half the Cajun seasoning, salt, and pepper. Sauté until browned and cooked through, about 5 7 minutes. Remove chicken from skillet and set aside.
Sauté Vegetables:
In the same skillet, add remaining olive oil and butter. Sauté onion and bell pepper for 3 4 minutes until softened. Add garlic and cook for 30 seconds until fragrant.
Add Seasoning and Cream:
Sprinkle in remaining Cajun seasoning and smoked paprika. Stir, then pour in the heavy cream. Bring to a gentle simmer, stirring frequently.
Add Cheese:
Add Parmesan cheese and stir until melted and sauce is smooth. Taste and adjust seasoning if needed.
Combine Chicken and Tortellini:
Return chicken to the skillet, along with cooked tortellini. Toss gently to coat everything in the sauce.
Finish and Serve:
Cook for an additional 2 3 minutes until heated through. Serve garnished with fresh parsley and extra Parmesan if desired.
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My family always gathers around the table for this meal, and it is especially popular on chilly evenings when something hearty and spicy is most welcome.

Required Tools

Large pot, large skillet, chefs knife, cutting board, wooden spoon or spatula, measuring cups and spoons

Notes

For extra heat, add a pinch of cayenne pepper or red pepper flakes. Substitute shrimp for chicken for a seafood twist. Serve with crusty bread and pair with crisp white wine.

Nutritional Information

Calories: 620 Protein: 38 g Carbohydrates: 53 g Total Fat: 29 g (per serving)

Sizzling Zesty Cajun Garlic Parmesan Chicken Tortellini, featuring vibrant colors and rich flavors.  Save
Sizzling Zesty Cajun Garlic Parmesan Chicken Tortellini, featuring vibrant colors and rich flavors. | tastyeffect.com

Enjoy every spicy, creamy bite with loved ones, and don&t forget extra Parmesan for the perfect finish.

Recipe FAQ

What protein can I use besides chicken?

Shrimp makes a great substitute for chicken. Sauté until pink and toss with the tortellini and sauce.

How spicy is this dish?

It has a mild Cajun heat. Adjust by adding cayenne or red pepper flakes for more spiciness.

Can I use dried tortellini instead of refrigerated?

Dried tortellini works, but follow package instructions for cooking time to ensure tenderness.

What sides pair well with this?

Crusty bread complements the creamy sauce, and a crisp salad or steamed vegetables work nicely.

Is this dish suitable for meal prep?

Yes, store leftovers in an airtight container in the fridge. Reheat gently and add a splash of cream for freshness.

Can I make this dairy-free?

Use dairy-free cream and Parmesan-style cheese alternatives for a suitable swap.

Zesty Cajun Garlic Parmesan Chicken

Chicken, tortellini, creamy Cajun garlic Parmesan sauce. Quick and vibrant, perfect for busy evenings.

Prep duration
15 min
Cook duration
25 min
Complete duration
40 min
Created by Laura Bennett


Skill level Easy

Heritage American/Italian Fusion

Output 4 Portions

Dietary requirements None specified

Components

Proteins

01 2 large boneless, skinless chicken breasts, cut into bite-sized pieces

Pasta

01 18 ounces refrigerated cheese tortellini

Vegetables & Aromatics

01 3 cloves garlic, minced
02 1 small red bell pepper, diced
03 1 small yellow onion, diced

Dairy

01 1 cup heavy cream
02 1/2 cup freshly grated Parmesan cheese
03 2 tablespoons unsalted butter

Spices & Seasonings

01 1 tablespoon Cajun seasoning
02 1/2 teaspoon smoked paprika
03 1/2 teaspoon black pepper
04 1/2 teaspoon salt, plus more to taste

Oils & Garnish

01 2 tablespoons olive oil
02 2 tablespoons chopped fresh parsley, for garnish
03 Extra grated Parmesan, optional for serving

Directions

Phase 01

Prepare the Tortellini: Fill a large pot with salted water and bring to a boil. Cook the cheese tortellini according to package directions. Drain well and set aside.

Phase 02

Sauté the Chicken: Warm 1 tablespoon olive oil in a large skillet over medium-high heat. Add the chicken and season using half the Cajun seasoning, salt, and black pepper. Sear and cook until golden and fully cooked, roughly 5-7 minutes. Transfer chicken to a plate.

Phase 03

Cook Aromatics: Utilizing the same skillet, add the remaining olive oil and butter. Sauté onion and bell pepper until softened, about 3-4 minutes. Stir in minced garlic and cook for 30 seconds until fragrant.

Phase 04

Build the Sauce: Sprinkle in the remaining Cajun seasoning and smoked paprika. Stir to combine, then pour in heavy cream and bring to a gentle simmer while stirring continually.

Phase 05

Finish Sauce: Introduce Parmesan cheese to the pan, stirring until completely melted to create a smooth sauce. Taste, and adjust seasoning as required.

Phase 06

Combine Ingredients: Return chicken and cooked tortellini to the skillet. Toss gently to coat everything evenly with the sauce.

Phase 07

Final Heating: Continue to cook for an additional 2-3 minutes, ensuring all components are heated through.

Phase 08

Serve and Garnish: Plate the dish and garnish with fresh chopped parsley and extra grated Parmesan, as preferred.

Necessary tools

  • Large pot
  • Large skillet
  • Chef's knife
  • Cutting board
  • Wooden spoon or spatula
  • Measuring cups and spoons

Allergy details

Review each component for potential allergens and seek professional healthcare advice if uncertain.
  • Contains wheat (tortellini), milk (cream, Parmesan, butter), eggs (tortellini may contain egg). Review tortellini packaging for additional allergens.

Nutritional information (per portion)

These values are approximate guides only and shouldn't replace professional medical consultation.
  • Energy: 620
  • Fats: 29 g
  • Carbohydrates: 53 g
  • Proteins: 38 g